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Tysabri

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Common known side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

- Body produces substance that can bind to drug making it less effective or cause side effects- cough- difficulty swallowing- dizziness- fast heartbeat- hives- itching- puffiness or swelling of the eyelids or around the eyes, face, lips or tongue- shortness of breath- skin rash- tightness in chest- unusual tiredness or weakness- wheezing

Rare

- Abdominal fullness- blurred vision- changes in behavior- chest pain- confusion- difficult or labored breathing- faintness, or lightheadedness when getting up from a lying or sitting position suddenly- feeling of warmth- feeling unusually cold- fever- gaseous abdominal pain- nausea- redness of the face, neck, arms and occasionally, upper chest- shivering- sneezing- sore throat- sweating- thoughts of killing oneself- troubled breathing- yellow eyes or skin

Frequency unknown

- Back pain- convulsions- drowsiness- headache

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More Common

- Bladder pain- blistering, crusting, irritation, itching, or reddening of skin- bloody or cloudy urine- cracked, dry, scaly skin- diarrhea- difficult, burning, or painful urination- difficulty in moving- discouragement- feeling sad or empty- frequent, strong or increased urge to urinate- headache- irregular menstruation- irritability- itching of the vagina or genital area- lack of appetite- loss of appetite- loss of interest or pleasure- lower back or side pain- muscle pain or stiffness- nausea- pain, cramps, heavy bleeding- pain during sexual intercourse- pain in joints- passing urine more often- stomach pain- stomach soreness or discomfort- swelling- swollen glands- thick, white vaginal discharge with no odor or with a mild odor- trouble concentrating- trouble sleeping

Less common

- Absent, missed, or irregular menstrual periods- chest discomfort- fainting- local bleeding- shakiness in legs, arms, hands, or feet- stopping of menstrual bleeding- trembling or shaking of hands or feet

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.