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- The proper way to use
- Precautions to keep in mind
- Common known side effects
Common known side effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Also, because of the way sirolimus acts on the body, there is a chance that it may cause effects that may not occur until years after the medicine is used. These delayed effects may include certain types of cancer, such as lymphoma.
Check with your doctor immediately if any of the following side effects occur:
More common
- Black or red, tarry stools- chest pain- general feeling of discomfort or illness- shortness of breath- swollen glands- weight loss, unusual- yellow skin and eyesCheck with your doctor as soon as possible if any of the following side effects occur:
More common
- Abdominal cramps or pain- accumulation of pus- anxiousness, unexplained- backache- bleeding from gums or nose- blindness- bloody or cloudy urine- blue lips and fingernails- blurred vision- body aches or pain- bone pain- bruising- burning or stinging of skin- burning while urinating- burning, dry, or itching eyes- burning, tingling, numbness, or pain in the hands, arms, feet, or legs- change in mental status- changes in skin color- chills- cold hands and feet- cold sweats- confusion- convulsions (seizures)- cough; cough producing mucus; cough that sometimes produces a pink frothy sputum- coughing up blood- dark or bloody urine- deafness- decreased urge to urinate- decreased urine output- decreased vision- difficult, fast, noisy breathing sometimes with wheezing- difficulty in breathing or swallowing- difficulty speaking- dilated neck veins- discharge from eye- dizziness- drowsiness- dry mouth- ear congestion- earache- excessive tearing- extreme fatigue- eye pain- facial hair growth in females- fainting- faintness or lightheadedness when getting up from lying or sitting position- fast, slow, or irregular heartbeat- fatigue- feeling faint- feeling of warmth or heat- fever- flushed, dry skin- flushing or redness of skin, especially on face and neck- fractures- frequent urge to urinate- fruit-like breath odor- full or round face, neck, or trunk- increased hunger- increased menstrual flow or vaginal bleeding- increased sweating- increased thirst- increased urination- irregular breathing- irritability- itching, pain, redness, swelling, tenderness, warmth on skin- lab results that show problems with liver- lack or loss of appetite- large, flat, blue or purplish patches in the skin- lightheadedness- loss of consciousness- loss of sexual ability, desire, drive, or performance- loss of voice- lower back or side pain- lump in abdomen- menstrual irregularities- mood changes- muscle cramps in hands, arms, feet, legs, or face- muscle pain- muscle wasting- nasal congestion- nausea or vomiting- noisy breathing- numbness or tingling around lips, hands, or feet- pain in chest, groin, or legs, especially the calves- pain, tenderness, swelling of foot or leg- painful blisters on trunk of body- painful cold sores or blisters on lips, nose, eyes, or genitals- painful or difficult urination- pale skin- paralysis- pinpoint red spots on skin- pounding or racing heartbeat or pulse- prolonged bleeding from cuts- pus in urine- rapid heartbeat- rapid, shallow breathing- rash- red or dark brown urine- redness or swelling in ear- redness, pain, swelling of eye, eyelid, or inner lining of eyelid- ringing in the ears- runny nose- sensation of pins and needles- severe constipation- severe vomiting- severe, sudden headache- slurred speech- sneezing- sore mouth or tongue- sore throat- sores or white spots on lips or in mouth- stabbing pain- stomach pain or upset- stomachache- sudden decrease in amount of urine- sudden loss of coordination- sudden, severe weakness or numbness in arm or leg- sudden, unexplained shortness of breath- sweating- swelling of face, fingers, hands, ankles, feet, or lower legs- swollen glands- swollen, painful or tender lymph glands in neck, armpit, or groin- swollen, red, tender area of infection- tenderness, pain, swelling, warmth, skin discoloration, and prominent superficial veins over affected area- tightness in chest- tiredness- tremor- trouble breathing- ulcers on lips or in mouth- unusual bleeding or bruising- unusual tiredness or weakness- vision changes- weakness- weakness or heaviness of legs- weight gain- wheezing- white patches in mouth and/or on tongueLess common
- Bloating- change is size, shape, or color of existing mole- darkened urine- hoarseness- mole that leaks fluid or bleeds- new mole- pains in stomach, side or abdomen, possibly radiating to the back- skin ulcer or soresRare
- Weight gain, unusualUnknown frequency
- Abnormal wound healing- hives- itching- large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs- nails loose or detached- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue- swelling of arms or legs- troubled breathing- yellow nails lacking a cuticleSome side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Abdomen enlarged- abnormal vision- acne- belching- blistering, crusting, irritation, itching, or reddening of skin- bloated full feeling- burning feeling in chest or stomach- burning, crawling, itching, numbness, prickling, "pins and needles" or tingling feeling- constipation- continuing ring or buzzing or other unexplained noise in ears- cracked, dry, scaly skin- crying- decrease in frequency of urination- decrease in height- decreased interest in sexual intercourse- degenerative disease of the joint- depersonalization- diarrhea- difficulty in moving- difficulty in passing urine [dribbling]- discouragement- dysphoria- ear pain- euphoria- excess air or gas in stomach or intestines- excessive muscle tone, muscle tension or tightness- fear- feeling sad or empty- headache- hearing loss- heartburn- inability to have or keep an erection- increase in heart rate- increased hair growth, especially on the face- increased urge to urinate during the night- indigestion- irritation in mouth- itching skin- joint pain or swelling- kidney pain- leg cramps- loss of bladder control- loss of energy or weakness- loss of interest or pleasure- loss of strength- lower abdominal pain- mental depression- muscle aches, pain, stiffness, or weakness- nervousness- pain- pain in back, ribs, arms, or legs- pain or burning in throat- pain or tenderness around eyes and cheekbones- paranoia- passing gas- pelvic pain- quick to react or overreact emotionally- rapid breathing- rapidly changing moods- inflammation, redness, or swelling of gums or mouth- shaking or trembling- shivering- sleepiness- sunken eyes- swelling- swelling of the scrotum- tender or enlarged gums- tenderness in stomach area- thickening of the skin- trouble concentrating- trouble in sleeping - waking to urinate at night- wrinkled skinOther side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
- The proper way to use
- Precautions to keep in mind
- Common known side effects
