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Methotrexate, abbreviated MTX and formerly known as amethopterin, is an antimetabolite drug used in treatment of cancer and autoimmune diseases. It acts by inhibiting the metabolism of folic acid. more at Wikipedia

Treatment Success Rate

Top 5 Communities
Condition Members Success
Rheumatoid Arthritis
360
81%
Lupus
166
70%
Arthritis
88
90%
Psoriasis
90
78%
Crohn's Disease & Ulcer...
54
57%
Overall, 79% (920 Members) find Methotrexate helpful

Methotrexate Reviews

Show: for
Working / Worked
no problems
Working / Worked
not working as well as it should
Working / Worked
Hard to remember to take each week, but easy to realize I forgot! It works.
I couldnt tell anything when I took methrotrexate.
it worked but i became suicidally depressed and very sick.
Working / Worked
Worked for years but I felt horrible the day after I took it. Nausea, lethargy, yuck!
Working / Worked
Just started 1 month ago. Not much help yet, just side effects
Working / Worked
In the 6th week, and seems to be helping some.
Working / Worked
Not strong enough alone. Slowly being taken off this med.
Working / Worked
YUCK
Working / Worked
12.5mg weekly. Seems to work the best but hasn't stopped my current flare.
His hair never came back 100% so about 4 years ago he decided to shave his head, which he looks good bald. He's now 57 years old.
Working / Worked
works, but causes her to be very sick for several days
Working / Worked
I've been using this medication since the beginning of my illness, in July 2004. I tried subcutaneous (injection) b/c it's been shown to absorb up to 80%, as opposed to around 20% with tablets, but the injections made me violently sick. So I'm back to tablets and the nasty side effects cleared up.
Working / Worked
terrible headaches, nausea, felt like body was deteriorating, aging fast.
Showing 46 - 60 of 1010 Reviews
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Discussions

  1. Discussion: methotrexate
    I've been on methotrexate for about 6 months now with the only side effect being a little fatigue. It doesn't help me much on its own, but does in co... [More]
  2. Discussion: Methotrexate
    I never took the methotrexate either ,One time I was so fed up with the preedisone I decide to take my self off big mistake I got real sick Fever ch... [More]
  3. Discussion: Methotrexate
    Hi, Renee I have been on methotrexate for almost 2 years now. I was very sick when I was taking the pill form. I had terrible headaches, diahrea, s... [More]
  4. Discussion: Methotrexate
    I HAVE NEVER TAKEN METHOTREXATE MYSELF, BUT I KNOW COMING OFF OF PREDNISONE TOO FAST CAN CAUSE YOU TO FEEL SICK, HAVE JOINT PAIN/ACHES. I KNOW MY DOCT... [More]
  5. Discussion: Methotrexate
    Hi I take methotrexate too. A couple words of wisdom. I was told to take it on a day when I don't have to go anywhere or do anything so that if the M ... [More]

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