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Methotrexate belongs to the group of medicines known as antimetabolites. It is used to treat cancer of the breast, head and neck, lung, blood, bone, and lymph, and tumors in the uterus. It may also be used to treat other kinds of cancer, as determined by your doctor.

Methotrexate blocks an enzyme needed by the... continue

Treatment Success Rate

Top 5 Communities
Condition Members Success
Rheumatoid Arthritis
284
82%
Lupus
142
72%
Arthritis
81
90%
Psoriasis
86
77%
Crohn's Disease & Ulcer...
46
57%
Overall, 80% (780 Members) find Methotrexate helpful

Methotrexate Reviews

Show: for
Working / Worked
not working as well as it should
I couldnt tell anything when I took methrotrexate.
Working / Worked
Worked for years but I felt horrible the day after I took it. Nausea, lethargy, yuck!
Working / Worked
Just started 1 month ago. Not much help yet, just side effects
Working / Worked
In the 6th week, and seems to be helping some.
Working / Worked
Not strong enough alone. Slowly being taken off this med.
Working / Worked
YUCK
Working / Worked
works, but causes her to be very sick for several days
Working / Worked
I've been using this medication since the beginning of my illness, in July 2004. I tried subcutaneous (injection) b/c it's been shown to absorb up to 80%, as opposed to around 20% with tablets, but the injections made me violently sick. So I'm back to tablets and the nasty side effects cleared up.
Working / Worked
terrible headaches, nausea, felt like body was deteriorating, aging fast.
Working / Worked
also helping
Working / Worked
Please see above
Working / Worked
Didn't work at all. Makes hair fall out.
Working / Worked
works well with hunira but makes me sick all 3-4 days a week. Heavy side effects with either just injections or as pill supplement with other drugs.
Working / Worked
I am self injecting once a week and home and have had no side effects. Though I do get nauseous on occasion. My doctor said I shouldn't since this formulation bypasses my stomach but I still do.
Showing 1 - 15 of 853 Reviews
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Discussions

  1. Discussion: Methotrexate
    I never took the methotrexate either ,One time I was so fed up with the preedisone I decide to take my self off big mistake I got real sick Fever ch... [More]
  2. Discussion: Methotrexate
    Hi, Renee I have been on methotrexate for almost 2 years now. I was very sick when I was taking the pill form. I had terrible headaches, diahrea, s... [More]
  3. Discussion: Methotrexate
    I HAVE NEVER TAKEN METHOTREXATE MYSELF, BUT I KNOW COMING OFF OF PREDNISONE TOO FAST CAN CAUSE YOU TO FEEL SICK, HAVE JOINT PAIN/ACHES. I KNOW MY DOCT... [More]
  4. Discussion: Methotrexate
    I was wondering if anyone had any adverse reactions to this drug? Since I have been taking it (2 months) while weaning off of the prednisone I have b... [More]
  5. Advice: Methotrexate???
    It really worked for me. But I developed pneumonia and they took me off it. It might not necessarily been from the methotrexate. I had mono at the ... [More]

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