Artane

What you should know before using

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatrics

Children may be especially sensitive to the effects of antidyskinetics. This may increase the chance of side effects during treatment.

Geriatric

Agitation, confusion, disorientation, hallucinations, memory loss, and mental changes are more likely to occur in elderly patients, who are usually more sensitive to the effects of antidyskinetics.

Studies on effects in pregnancy have not been done in either humans or animals. However, antidyskinetics have not been shown to cause problems in humans.

Breast Feeding

It is not known if antidyskinetics pass into breast milk. Although most medicines pass into breast milk in small amounts, many of them may be used safely while breast-feeding. Mothers who are taking these medicines and who wish to breast-feed should discuss this with their doctor.

Since antidyskinetics tend to decrease the secretions of the body, it is possible that the flow of breast milk may be reduced in some patients.

Drug Interactions

Using medicines in this class with any of the following medicines is not recommended. Your doctor may decide not to treat you with a medication in this class or change some of the other medicines you take.

• Amphetamine
• Clorgyline
• Cyclobenzaprine
• Dextromethorphan
• Duloxetine
• Ephedrine
• Fluvoxamine
• Iproniazid
• Isocarboxazid
• Lisdexamfetamine
• Meperidine
• Methadone
• Mirtazapine
• Morphine
• Morphine Sulfate Liposome
• Nialamide
• Pargyline
• Phenelzine
• Phenylephrine
• Phenylpropanolamine
• Procarbazine
• Propoxyphene
• Pseudoephedrine
• Selegiline
• St John's Wort
• Toloxatone
• Tramadol
• Tranylcypromine

Using medicines in this class with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Apomorphine
• Bitolterol
• Desipramine
• Difenoxin
• Diphenoxylate
• Dobutamine
• Dopamine
• Epinephrine
• Fentanyl
• Fluoxetine
• Iproniazid
• Isocarboxazid
• Isoetharine
• Isoniazid
• Isoproterenol
• Linezolid
• Methyldopa
• Moclobemide
• Nialamide
• Norepinephrine
• Pargyline
• Paroxetine
• Phenelzine
• Procarbazine
• Sertraline
• Tranylcypromine
• Venlafaxine

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using medicines in this class with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use your medicine, or give you special instructions about the use of food, alcohol, or tobacco.

• Tyramine Containing Food

Other Medical Problems

The presence of other medical problems may affect the use of medicines in this class. Make sure you tell your doctor if you have any other medical problems, especially:

• Difficult urination or
• Enlarged prostate or
• Glaucoma or
• Heart or blood vessel disease or
• High blood pressure or
• Intestinal blockage or
• Myasthenia gravis or
• Uncontrolled movements of hands, mouth, or tongue—Antidyskinetics may make the condition worse.

• Kidney disease or
• Liver disease—Higher blood levels of the antidyskinetics may result, increasing the chance of side effects.