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Thrombocytopenic Purpura Support Group

Topics Replies Last Post
Latest platelet count 
1 By Becks12
05/06/08
What triggers a flare up ... 
1 By Tia0241
05/02/08
HPV Vac any problems? 
0 By jangail
04/13/08
OK, ITP is rareso lets ta... 
31 By Tia0241
04/11/08
Has anyone tried the ritu... 
3 By gabby216
03/25/08
Genetic itp 
1 By talon331
03/12/08

Thrombocytopenic Purpura Information

Thrombocytopenic purpura are purpura associated with a reduction in circulating blood platelets which can result from a variety of causes.

There are two known types:

Idiopathic thrombocytopenic purpura (ITP) is the condition of having a low platelet count (thrombocytopenia) of no known cause (idiopathic). As most causes appear to be related to antibodies against platelets, it is also known as immune thrombocytopenic purpura. Although most cases are asymptomatic, very low platelet counts can lead to a bleeding diathesis and purpura.

Thrombotic thrombocytopenic purpura (TTP or Moschcowitz disease) is a rare disorder of the blood coagulation system that in most cases arises from the deficiency or inhibition of the enzyme ADAMTS13, which is responsible for cleaving large multimers of von Willebrand factor. It is a serious condition that leads to hemolysis and end-organ damage, and may require plasmapheresis therapy.

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