What is Multiple Sclerosis MS

Multiple sclerosis (MS) is a chronic disease which affects the brain and spinal cord. MS can cause a variety of symptoms, including changes in sensation, visual problems, muscle we...

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B12-Synthesis of myelin sheath
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Many people with MS seem to have Lack of B12 and Vit D. This blog is to look into the lack of B12.

http://www.healthline.com/adamcont...
This link states that a metabolic problem of lack of Vit B12 can cause nerve damage.

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TEST
The BEST indicator or B12 deficiency is to ask your doctor to run a test to find out what your MMA (mehylmalonic Acid) levels are. If they are elevated you most probably have lack of B12.

B12 What it does:
Vitamin B12 works WITH folic acid in many body processes including SYNTHESIS of DNA, red blood cells and the insulation sheath (the myelin sheath) that surrounds nerve cells and facilitates the conduction of signals in the nervous system. Severe depletion manifests as pernicious anemia, which was invariably fatal until the discovery of B12 in liver. But long before anemia sets in, other conditions may manifest, most often neurological problems (numbness, pins and needles sensations, a burning feeling in the feet, shaking, muscle fatigue, sleep disorders, memory loss, irrational anger, impaired mental function and Alzheimer’s) or psychological conditions (dementia, depression, psychosis and obsessive-compulsive behavior).

B12 HELPS
1.)Produce melatonin which HELPS you sleep
2.)Useful adjunct for diabetics
3.)Have been helpful for those with Asthma(sulfite sensitivity), eczema, psorsis, osteporosis, Lupus and MS.
4.)Plus Low B12 resutls in Low antibody response, impaired immunity and increaese in infections (MS viral/bacteria cause??)

B12 & MS
One condition that would seem obviously correlated with B12 deficiency is multiple sclerosis (MS), a disease characterized by demyelination of the central nervous system. Yet many studies indicate that those with MS have normal blood levels of the vitamin. Japanese researchers have found that in MS patients, there is a decrease in the binding capacity of B12, thus inhibiting the transport of B12 into the cells, even in patients with normal levels in their blood. Even so, they were able to achieve some improvement with high-dose supplementation.
The benefit of B12 for depression may be due to B12’s ability to activate a substance called tetrahydrobiopterin (BH4), a compound which in turn helps activate "feel good" neurotransmitters like serotonin and DOPAmine.


How to GET More B12 + Stop the loss of B12
1.) Eat Liver or shellfish (High in B12). Steak is good but get it on the rarer side as it preserves more of the B12.
2.) Eat Calcium such as Unpasteurized proteins help B12 absorbtion so does Bone broths that heal intestinal inflam. and increase absorption.
3.) Take coconut oil and consume lacto-fermented foods: these help fight against pathogens such as helicobacter pylori, which is associated with B12 deficiency. Eradication of the organism often clears up B12 deficiency.

AVOID
1.)AVOID OVERconsumption of foods that BLOCK vitamin B12 intake or increase the body’s need for the vitamin, such as SOY foods and spirulina.
2.)Antacids and drugs that lower stomach acid levels: acid-suppressing drugs such as Tagamet, Zantac and Losec can lead to serious B12 deficiency
3.) Foods fortified with folic acid. Taking folic acid withOUT B12 can mask signs of B12 deficiency in red blood cells but will not protect against deficiencies in the nervous system. Folic acid and B12 WORK WELL TOGETHER and any supplementation program should include BOTH of these nutrients (Institute of Medicine.National Academy Press. Washington, DC 1998).
4.)Avoid taking EXCESS vitamin C(normal amount fine), especially for long periods. The ability of vitamin C to destroy B12 has been observed by several researchers--although this is disputed by others. Small amounts of natural vitamin C are a better choice than large amounts of synthetic vitamin C.
5.) Avoid smoking, vaccinations containing thimerosol (ie flue shot) that contain mercury & oral contraception which all deplete B12
6.) Avoid mycotoxins made by molds that interfere with B12 functions. As well as pesticides and xenotoxins.

Since vitamin B12 in supplements is produced in exactly the same way as B12 in nature, that is, by bacterial fermentation, the danger of high doses in most cases is negligible.

More Info on Vit B12 found below:
http://www.westonaprice.org/basicn...
Posted on 05/07/08, 10:05 am
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Reply #11 - 05/07/08  1:52pm
" Proper B12 in blood may not mean in your tissues.
B12 needs coenzymes to transport it to the cells where it can be used. Much the same way you need iron in your hemiglobin to transport oxyagen to your cells so you can break down nutrients for energy.

Have you ever had a MMR to see if your tissues are depleted in B12?? "
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Reply #12 - 05/07/08  2:05pm
" Nope, no MMR here. "
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Reply #13 - 05/07/08  2:06pm
" what is an MMR? only thing I find is about MMR is measles, mumps and rubella "
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Reply #14 - 05/07/08  2:09pm
" Vitamin B12, Serum ng/L 200-1100 range 541 result
Folate, Serum ng/mL > 5.4 range >24 result "
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Reply #15 - 05/07/08  2:12pm
" oh, this is interesting.. my B12s are actually going up since adding B1 100 to my diet 7/05

Vitamin B12, Serum ng/L 200-1100
1/11/05 337
2/21/06 421
6/13/06 485
1/09/08 541 "
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Reply #16 - 05/07/08  2:23pm
" My bad an MMA see the original post. The test mentioned at the top. It is NOT done on blood but your tissues. Ever had this done.. I'd like to see the results of MMA as opposed to blood results that you have posted. This way it if tissue comes back OK for B12 less credit to this theory. If it comes back LOW when blood is fine...might give some credit to this theory. "
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Reply #17 - 05/07/08  2:35pm
" oh, MMA. how's the test done? I'm not one to be a guinea pig when they play Gumby and POKEY on my body.

anyone else get MMA done? "
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Reply #18 - 05/07/08  2:37pm
" I have a question,
I may be wrong but I thought MS damage was caused by an overactive autoimmune system. It forgets to turn off and starts to attack it's own body.
So, if we take vitamins and extra supplements that boost the immune system, would'nt that just make it worse.?

Sorry if this is a dumb question. "
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Reply #19 - 05/07/08  2:48pm
" as you and i have already disucussed eczema..i have pernicious amemia (B-12) definciay and was dx with that before i got the dx of ms..it came about becuase my epilesy neuro was checking my potasium levels which was fine...
he was looking for an explaintion for the tingling..grin..had he have read the mri's back then..he would have known...rofl..by the way..thx again for all the info...smile

hugs
heather "
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Reply #20 - 05/07/08  2:51pm
" I think we have different reasons for our MS's... I believe MS is a Result, not a Cause, or maybe even an Effect.

I think you get MS when the body is under attack and the immune system just CAN'T do it's job. Whether it's overactive and run amuck is one thing, if it just can't keep up with an attack, that's another.

They really don't know, there are too many unseen factors.

But, yes, if you're not on something helping your immune system, adding Fuel to that kind of fire could make it worse... like Echenacia or CoQ10 shouldn't be taken if your immune system is wacky.

I feel once on LDN and back to a stable homeostasis, then whatever you take would work well.. the key being not to OD on anything thinking you need MORE.

Everyone has to figure out their own situation. I recently learned more of where and why I have MS, I Just have the after effects due to the permanent damage caused, leaving multiple scars where myelin sheeth used to be. "
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